ATF5 ELISA Kit
Product Sizes
96 Wells
£814.00
OKEI00138-96WELLS
About this Product
- SKU:
- OKEI00138
- Additional Names:
- ATFX; HMFN0395
- Extra Details:
- Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'); ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE); present in many viral and cellular promoters. Critically involved; often in a cell type-dependent manner; in cell survival; proliferation; and differentiation . Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4 . Important regulator of the cerebral cortex formation; functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons. Must be down-regulated in order for such cells to exit the cycle and differentiate.
- Protein Details:
- Cyclic AMP-dependent transcription factor ATF-5
- Sensitivity:
- 0.188 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store as indicated in product manual.
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
