TNFA ELISA Kit
Product Sizes
48T
£727.00
OKDD06882-48T
96 Wells
£1016.00
OKDD06882-96WELLS
About this Product
- SKU:
- OKDD06882
- Additional Names:
- Cachectin;TNF-a;TNFA;TNF-alpha;TNFSF2;tumor necrosis factor;tumor necrosis factor ligand superfamily member 2;tumor necrosis factor-alpha.
- Extra Details:
- Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia; Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6 (By similarity).
- Gene Details:
- tumor necrosis factor
- Protein Details:
- Tumor necrosis factor
- Sensitivity:
- 6.9pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 12 months shelf life. For unopened kits: All the reagents should be kept at 4C upon receipt.
For opened kits: Once the kit is opened; the remaining reagents still need to be stored according to the above storage conditions. In addition; return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal. - Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
