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Assay Kits & ELISAs

IL28B ELISA Kit

Product Sizes
48T
£615.00
OKDD04061-48T
96 Wells
£890.00
OKDD04061-96WELLS
About this Product
SKU:
OKDD04061
Additional Names:
cytokine Zcyto22;IFN-lambda-3;IFN-lambda-4;IL28B;IL-28B;IL28C;IL-28C;interferon lambda-3;interferon; lambda 4;interleukin-28B;interleukin-28C.
Extra Details:
Cytokine with antiviral; antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense; predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1; and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG); which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection; but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Gene Details:
interferon lambda 3
Protein Details:
Interferon lambda-3
Sensitivity:
5.6pg/mL
Shipping Conditions:
Blue Ice
Storage Conditions:
12 months shelf life. For unopened kits: All the reagents should be kept at 4C upon receipt.
For opened kits: Once the kit is opened; the remaining reagents still need to be stored according to the above storage conditions. In addition; return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs