IRF9 ELISA Kit
Product Sizes
96T
£901.00
OKDD00345-96T
About this Product
- SKU:
- OKDD00345
- Additional Names:
- IFN-alpha-responsive transcription factor subunit;interferon regulatory factor 9;interferon-stimulated gene factor 3 gamma;interferon-stimulated transcription factor 3; gamma (48kD);interferon-stimulated transcription factor 3; gamma 48kDa;IRF-9;ISGF3;ISGF-3 gamma;ISGF3 p48 subunit;ISGF3G;p48;transcriptional regulator ISGF3 subunit gamma.
- Extra Details:
- Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors; Jak kinases (TYK2 and JAK1) are activated; leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor; that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes; which drive the cell in an antiviral state.
- Gene Details:
- interferon regulatory factor 9
- Molecular Weight:
- 44 kDa
- Protein Details:
- Interferon regulatory factor 9
- Sensitivity:
- < 0.042 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store as indicated in product manual.
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
