ATG5 ELISA Kit
Product Sizes
96 Wells
£955.00
OKCD09286-96WELLS
About this Product
- SKU:
- OKCD09286
- Additional Names:
- APG5;APG5 autophagy 5-like;APG5L;APG5-LIKE;apoptosis-specific protein;ASP;ATG5 autophagy related 5 homolog;autophagy protein 5;hAPG5;SCAR25.
- Extra Details:
- Involved in autophagic vesicle formation. Conjugation with ATG12; through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme; is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage; and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures; as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
- Gene Details:
- autophagy related 5
- Protein Details:
- Autophagy protein 5
- Sensitivity:
- < 0.28ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
