AIM2 ELISA Kit
Product Sizes
96 Wells
£1016.00
OKCD08905-96WELLS
About this Product
- SKU:
- OKCD08905
- Additional Names:
- Absent in melanoma 2;interferon-inducible protein AIM2;PYHIN4.
- Extra Details:
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent; caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
- Gene Details:
- absent in melanoma 2
- Protein Details:
- Interferon-inducible protein AIM2
- Sensitivity:
- < 0.063ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
