DAPK3 ELISA Kit
Product Sizes
96 Wells
£1042.00
OKCD08748-96WELLS
About this Product
- SKU:
- OKCD08748
- Additional Names:
- DAP kinase 3;DAP-like kinase;death-associated kinase 3;death-associated protein kinase 3;dlk;MYPT1 kinase;ZIPK;ZIP-kinase.
- Extra Details:
- Serine/threonine kinase which is involved in the regulation of apoptosis; autophagy; transcription; translation and actin cytoskeleton reorganization. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal; depending on the cellular setting. Involved in formation of promyelocytic leukemia protein nuclear body (PML-NB). Involved in apoptosis involving PAWR which mediates cytoplasmic relocation; in vitro phosphorylates PAWR (By similarity). Phosphorylates MYL12B in non-muscle cells leading to reorganization of actin cytoskeleton such as in regulation of cell polarity and cell migration. Positively regulates canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2; disrupts the NLK-TCF7L2 complex thereby influencing the phosphorylation of TCF7L2 by NLK. Phosphorylates STAT3 and enhances its transcriptional activity. Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis (By similarity). Phosphorylates RPL13A on 'Ser-77' upon interferon-gamma activation which is causing RPL13A release from the ribosome; RPL13A association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition.
- Gene Details:
- death-associated protein kinase 3
- Protein Details:
- Death-associated protein kinase 3
- Sensitivity:
- < 0.058ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
