HTR2A ELISA Kit
Product Sizes
96 Wells
£1016.00
OKCD08491-96WELLS
About this Product
- SKU:
- OKCD08491
- Additional Names:
- 5-HT2 receptor;5-HT2A;5-hydroxytryptamine (serotonin) receptor 2A; G protein-coupled;5-hydroxytryptamine receptor 2A;HTR2;serotonin 5-HT-2A receptor;Serotonin receptor 2A.
- Extra Details:
- G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647; PubMed:18703043; PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances; including mescaline; psilocybin; 1-(2;5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (PubMed:18703043; PubMed:28129538). Affects neural activity; perception; cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior; including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction; and may play a role in arterial vasoconstriction.
- Gene Details:
- 5-hydroxytryptamine receptor 2A
- Protein Details:
- 5-hydroxytryptamine receptor 2A
- Sensitivity:
- < 0.065ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
