CUBN ELISA Kit
Product Sizes
96 Wells
£1070.00
OKCD08116-96WELLS
About this Product
- SKU:
- OKCD08116
- Additional Names:
- 460 kDa receptor;cubilin;glycoprotein 280;GP280;IFCR;intrinsic factor-cobalamin receptor;intrinsic factor-vitamin B12 receptor;MGA1.
- Extra Details:
- Cotransporter which plays a role in lipoprotein; vitamin and iron metabolism; by facilitating their uptake. Binds to ALB; MB; Kappa and lambda-light chains; TF; hemoglobin; GC; SCGB1A1; APOA1; high density lipoprotein; and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia; including intestine; renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC; hemoglobin; ALB; TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
- Gene Details:
- cubilin
- Protein Details:
- Cubilin
- Sensitivity:
- < 0.114ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
