GDF5 ELISA Kit
Product Sizes
96 Wells
£842.00
OKCD07997-96WELLS
About this Product
- SKU:
- OKCD07997
- Additional Names:
- BDA1C;BMP14;BMP-14;bone morphogenetic protein 14;Cartilage-derived morphogenetic protein 1;cartilage-derived morphogenetic protein-1;CDMP1;DUPANS;growth/differentiation factor 5;LAP4;LAP-4;lipopolysaccharide-associated protein 4;LPS-associated protein 4;OS5;radotermin;SYM1B;SYNS2.
- Extra Details:
- Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly; positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A; leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction (PubMed:24098149; PubMed:21976273; PubMed:15530414; PubMed:25092592). Secondly; negatively regulates chondrogenic differentiation through its interaction with NOG (PubMed:21976273). Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (By similarity). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response; including TNF secretion by monocytes (PubMed:11276205).
- Gene Details:
- growth differentiation factor 5
- Protein Details:
- Growth/differentiation factor 5
- Sensitivity:
- < 6.7pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
