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Assay Kits & ELISAs

MKI67 ELISA Kit

Product Sizes
96 Wells
£1016.00
OKCD07952-96WELLS
About this Product
SKU:
OKCD07952
Additional Names:
antigen identified by monoclonal antibody Ki-67;antigen Ki67;KIA;MIB-;MIB-1;Molecular Immunology Borstel antibody 1;PPP1R105;proliferation marker protein Ki-67;proliferation-related Ki-67 antigen;protein phosphatase 1; regulatory subunit 105.
Extra Details:
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome; the perichromosomal layer; and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant; dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA; with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
Gene Details:
marker of proliferation Ki-67
Protein Details:
Proliferation marker protein Ki-67
Sensitivity:
< 0.32ng/mL
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs