OLR1 ELISA Kit
Product Sizes
96 Wells
£1042.00
OKCD07740-96WELLS
About this Product
- SKU:
- OKCD07740
- Additional Names:
- lectin-like oxidized LDL receptor 1;lectin-like oxidized low-density lipoprotein receptor;Lectin-like oxidized low-density lipoprotein receptor-1;lectin-like oxLDL receptor 1;lectin-type oxidized LDL receptor 1;LOX-1;Oldlr1;Oldr1;oxidised low density lipoprotein (lectin-like) receptor 1;oxidized low density lipoprotein (lectin-like) receptor 1;oxidized low-density lipoprotein receptor 1;ox-LDL receptor 1.
- Extra Details:
- Receptor that mediates the recognition; internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction; resulting in pro-inflammatory responses; pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release; monocyte adhesion and apoptosis. In addition to binding oxLDL; it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells; thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process; by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products; activated platelets; monocytes; apoptotic cells and both Gram-negative and Gram-positive bacteria.
- Gene Details:
- oxidized low density lipoprotein receptor 1
- Protein Details:
- Oxidized low-density lipoprotein receptor 1
- Sensitivity:
- < 22.5pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
