KNG1 ELISA Kit

Product Sizes

96 Wells

£955.00

OKCD07673-96WELLS

About this Product

SKU:: OKCD07673
Additional Names:: alpha-2-thiol proteinase inhibitor;BDK;BK;bradykinin;fitzgerald factor;HAE6;high molecular weight kininogen;HMWK;kininogen-1;KNG;williams-Fitzgerald-Flaujeac factor.
Extra Details:: (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction; (4B) induction of hypotension; (4C) natriuresis and diuresis; (4D) decrease in blood glucose level; (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability; (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins); (4F) it has a cardioprotective effect (directly via bradykinin action; indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Gene Details:: kininogen 1
Protein Details:: Kininogen-1
Sensitivity:: < 1.31ng/mL
Shipping Conditions:: Blue Ice
Storage Conditions:: 2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:: Aviva Systems Biology
Type:: Assay Kits: ELISAs

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