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Assay Kits & ELISAs

ITGAL ELISA Kit

Product Sizes
96 Wells
£842.00
OKCD07502-96WELLS
About this Product
SKU:
OKCD07502
Additional Names:
(p180);alpha L integrin;Cd11;CD11 antigen-like family member A;Cd11a;integrin alpha-L;leukocyte adhesion glycoprotein LFA-1 alpha chain;leukocyte function-associated molecule 1 alpha chain;LFA;LFA-1;LFA-1A;Ly-1;Ly-15;Ly-2;Ly-21;lymphocyte antigen 15;lymphocyte function associated antigen 1; alpha polypeptide.
Extra Details:
Integrin ITGAL/ITGB2 is a receptor for ICAM1; ICAM2; ICAM3 and ICAM4 (PubMed:2051027). Integrin ITGAL/ITGB2 is a receptor for F11R (By similarity). Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL (PubMed:29100055). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction; cytotoxic T-cell mediated killing; and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:16234355; PubMed:24158516). Required for generation of common lymphoid progenitor cells in bone marrow; indicating the role in lymphopoiesis (PubMed:25108025). Integrin ITGAL/ITGB2 in association with ICAM3; contributes to apoptotic neutrophil phagocytosis by macrophages.
Gene Details:
integrin alpha L
Protein Details:
Integrin alpha-L
Sensitivity:
< 0.054ng/mL
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs