BAX ELISA Kit
Product Sizes
96 Wells
£1042.00
OKCD07340-96WELLS
About this Product
- SKU:
- OKCD07340
- Additional Names:
- apoptosis regulator BAX;BCL2-associated X protein.
- Extra Details:
- Accelerates programmed cell death by binding to; and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions; undergoes a conformation change that causes translocation to the mitochondrion membrane; leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3; and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility; because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domain); inhibits BAX activation and translocation and consequently cytochrome c release from mitochondria (By similarity).
- Gene Details:
- BCL2 associated X; apoptosis regulator
- Protein Details:
- Apoptosis regulator BAX
- Sensitivity:
- < 4.6pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
