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Assay Kits & ELISAs

A2M ELISA Kit

Product Sizes
96 Wells
£1042.00
OKCD07060-96WELLS
About this Product
SKU:
OKCD07060
Additional Names:
A2m1;A2maa;A2MAC1;A2mb;alpha-2-M;alpha-2-macroglobulin;alpha-2-macroglobulin-P;Mam.
Extra Details:
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch; called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region; a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Gene Details:
alpha-2-macroglobulin|alpha-2-macroglobulin-like
Protein Details:
Alpha-2-macroglobulin
Sensitivity:
< 5.9ng/mL
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs