RUNX2 ELISA Kit
Product Sizes
96 Wells
£955.00
OKCD07056-96WELLS
About this Product
- SKU:
- OKCD07056
- Additional Names:
- acute myeloid leukemia 3 protein;AML3;CBFA1;CBF-alpha-1;CCD;CCD1;CLCD;Core-binding factor subunit alpha-1;core-binding factor; runt domain; alpha subunit 1;oncogene AML-3;OSF2;OSF-2;osteoblast-specific transcription factor 2;PEA2aA;PEA2-alpha A;PEBP2aA;PEBP2-alpha A;polyomavirus enhancer-binding protein 2 alpha A subunit;runt related transcription factor 2;runt-related transcription factor 2;SL3/AKV core-binding factor alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit.
- Extra Details:
- Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335; PubMed:28738062; PubMed:28703881). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site; 5'-PYGPYGGT-3'; of a number of enhancers and promoters; including murine leukemia virus; polyomavirus enhancer; T-cell receptor enhancers; osteocalcin; osteopontin; bone sialoprotein; alpha 1(I) collagen; LCK; IL-3 and GM-CSF promoters. In osteoblasts; supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
- Gene Details:
- RUNX family transcription factor 2
- Protein Details:
- Runt-related transcription factor 2
- Sensitivity:
- < 0.057 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
