Anti-MAG ELISA Kit
Product Sizes
96 Wells
£1070.00
OKCD04530-96WELLS
About this Product
- SKU:
- OKCD04530
- Additional Names:
- GMA;myelin-associated glycoprotein;sialic acid binding Ig-like lectin 4A;sialic acid-binding immunoglobulin-like lectin 4A;SIGLEC4A;SIGLEC-4A;S-MAG;SPG75.
- Extra Details:
- Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). Not required for initial myelination; but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis; also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane (By similarity). Negative regulator of neurite outgrowth; in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons; inhibition of neurite extension depends only partially on RTN4R; RTN4RL2 and gangliosides. Inhibits axon longitudinal growth (By similarity). Inhibits axon outgrowth by binding to RTN4R (By similarity). Preferentially binds to alpha-2;3-linked sialic acid. Binds ganglioside Gt1b (By similarity).
- Gene Details:
- myelin associated glycoprotein
- Protein Details:
- Myelin-associated glycoprotein
- Sensitivity:
- < 0.59ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
