IFNL2 Chemi-Luminescent ELISA Kit
Product Sizes
96 Wells
£1070.00
OKCD03664-96WELLS
About this Product
- SKU:
- OKCD03664
- Additional Names:
- EG330496;If1ia1;IFN-lambda2;IFN-lambda-2;Il;Il28a;IL-28A;interferon 1ia1;interferon lambda-2;interferon-lambda2;interleukin-28A.
- Extra Details:
- Cytokine with antiviral; antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense; predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1; and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG); which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection; but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- Gene Details:
- interferon lambda 2
- Protein Details:
- Interferon lambda-2
- Sensitivity:
- 15.6 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
