RUNX2 ELISA Kit
Product Sizes
96 Wells
£842.00
OKCD02856-96WELLS
About this Product
- SKU:
- OKCD02856
- Additional Names:
- acute myeloid leukemia 3 protein;AKV core binding factor;AM;AML3;Cbf;Cbfa;Cbfa1;Cbfa-1;CBF-alpha-1;core binding factor alpha 1;Core-binding factor subunit alpha-1;LS3;Oncogene AML-3;Os;Osf2;osteoblast-specific transcription factor 2;PEA2-alpha A;PEB;PEBP2 alpha A;Pebp2a1;PEBP2aA;Pebpa2a;polyomavirus enhancer-binding protein 2 alpha A subunit;runt domain; alpha subunit 1;runt-related transcription factor 2;SL3/AKV core-binding factor alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit;transcription factor Cbfa1/Osf2.
- Extra Details:
- Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site; 5'-PYGPYGGT-3'; of a number of enhancers and promoters; including murine leukemia virus; polyomavirus enhancer; T-cell receptor enhancers; osteocalcin; osteopontin; bone sialoprotein; alpha 1(I) collagen; LCK; IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation (By similarity). In osteoblasts; supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
- Gene Details:
- runt related transcription factor 2
- Protein Details:
- Runt-related transcription factor 2
- Sensitivity:
- 0.116 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
