PSMB8 ELISA Kit
Product Sizes
96 Wells
£842.00
OKCD02695-96WELLS
About this Product
- SKU:
- OKCD02695
- Additional Names:
- ALDD;D6S216;D6S216E;JMP;LMP7;low molecular mass protein 7;low molecular weight protein 7;macropain subunit C13;multicatalytic endopeptidase complex subunit C13;NKJO;PRAAS1;protease component C13;proteasome (prosome; macropain) subunit; beta type; 8 (large multifunctional peptidase 7);proteasome catalytic subunit 3i;proteasome component C13;proteasome subunit beta 5i;proteasome subunit beta 8;proteasome subunit beta type-8;Proteasome subunit beta-5i;proteasome subunit Y2;proteasome-related gene 7;PSMB5i;really interesting new gene 10 protein;RING10.
- Extra Details:
- The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg; Phe; Tyr; Leu; and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells; substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes.
- Gene Details:
- proteasome 20S subunit beta 8
- Protein Details:
- Proteasome subunit beta type-8
- Sensitivity:
- 0.117 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
