BMX ELISA Kit
Product Sizes
96 Wells
£955.00
OKCD02404-96WELLS
About this Product
- SKU:
- OKCD02404
- Additional Names:
- bone marrow tyrosine kinase gene in chromosome X protein homolog;cytoplasmic tyrosine-protein kinase BMX;Etk;Etk/Bmx;Tyr;Tyro8;TYRO8 protein tyrosine kinase 8.
- Extra Details:
- Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization; cell migration; cell proliferation and survival; cell adhesion; and apoptosis. Participates in signal transduction stimulated by growth factor receptors; cytokine receptors; G-protein coupled receptors; antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1; a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis; and implicated in the signaling of TEK and FLT1 receptors; 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3; a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems; salivary epithelial cells; brain endothelial cells; and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells.
- Gene Details:
- BMX non-receptor tyrosine kinase
- Protein Details:
- Cytoplasmic tyrosine-protein kinase BMX
- Sensitivity:
- 0.113 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
