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Assay Kits & ELISAs

ADAM17 ELISA Kit

Product Sizes
96 Wells
£868.00
OKCD02340-96WELLS
About this Product
SKU:
OKCD02340
Additional Names:
CD156b;disintegrin and metalloproteinase domain-containing protein 17;Tac;Tace;TNF-alpha convertase;TNF-alpha converting enzyme;TNF-alpha-converting enzyme.
Extra Details:
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Plays a role in the proteolytic processing of ACE2 (By similarity). Responsible for the proteolytic release of several other cell-surface proteins; including p75 TNF-receptor; interleukin 1 receptor type II; p55 TNF-receptor; transforming growth factor-alpha; L-selectin; growth hormone receptor; MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch; generating the membrane-associated intermediate fragment called notch extracellular truncation (NEXT).
Gene Details:
a disintegrin and metallopeptidase domain 17
Protein Details:
Disintegrin and metalloproteinase domain-containing protein 17
Sensitivity:
0.054 ng/mL
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs