ADAM17 ELISA Kit
Product Sizes
96 Wells
£901.00
OKCD02296-96WELLS
About this Product
- SKU:
- OKCD02296
- Additional Names:
- a disintegrin and metallopeptidase domain 17;a disintegrin and metalloprotease domain 17;a disintegrin and metalloproteinase domain 17 (tumor necrosis factor; alpha; converting enzyme);ADAM 17;disintegrin and metalloproteinase domain-containing protein 17;TACE;TNF-alpha convertase;TNF-alpha-converting enzyme.
- Extra Details:
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins; including p75 TNF-receptor; interleukin 1 receptor type II; p55 TNF-receptor; transforming growth factor-alpha; L-selectin; growth hormone receptor; MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch; generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2 (By similarity).
- Gene Details:
- ADAM metallopeptidase domain 17
- Protein Details:
- Disintegrin and metalloproteinase domain-containing protein 17
- Sensitivity:
- 0.061 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
