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Assay Kits & ELISAs

1;5-Anhydroglucitol ELISA Kit

Product Sizes
96 Wells
£983.00
OKCD02247-96WELLS
About this Product
SKU:
OKCD02247
Additional Names:
1 1;5-Anhydro-D-glucitol; 1;5-Anhydroglucitol; 154-58-5; 1;5-ANHYDROSORBITOL
Extra Details:
1; 5-Anhydrosorbitol or 1; 5-anhydroglucitol (1; 5-AG) is a validated marker of short-term glycemic control. This substance is derived mainly from food; is well absorbed in the intestine; and is distributed to all organs and tissues. It is metabolically stable; being excreted in the urine when its level exceeds the renal threshold. It is reabsorbed in the renal tubules and is competitively inhibited by glucosuria; which leads to a reduction in its level in serum. The correlation between this reduction and the amount of glucose present in urine is so close that 1; 5 AG can be used as a sensitive; day-to-day; real-time marker of glycemic control. It provides useful information on current glycemic control and is superior to both hemoglobin A1C and fructosamine in detecting near-normoglycemia. 1; 5-AG in human plasma has been proposed for several years as a short-term; retrospective marker of glycemic control and seems to be the most suitable parameter for monitoring glucose excursions. The decrease in serum 1; 5-AG is very sensitive to urinary glucose excretion. It is a metabolically inert polyol that competes with glucose for reabsorption in the kidneys. Otherwise stable levels of 1; 5-AG are rapidly depleted as blood glucose levels exceed the renal threshold for glucosuria. 1; 5-AG is also more tightly associated with glucose fluctuations and postprandial glucose.
Protein Details:
1;5-Anhydroglucitol
Sensitivity:
< 0.7 ug/mL
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs