UBA52 ELISA Kit
Product Sizes
96 Wells
£868.00
OKCD01827-96WELLS
About this Product
- SKU:
- OKCD01827
- Additional Names:
- CEP52;HUBCEP52;L40;RPL40;Ubiquitin A-52 residue ribosomal protein fusion product 1;ubiquitin carboxyl extension protein 52;ubiquitin-52 amino acid fusion protein;ubiquitin-60S ribosomal protein L40;ubiquitin-CEP52.
- Extra Details:
- Ubiquitin: Exists either covalently attached to another protein; or free (unanchored). When covalently bound; it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin); a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains; when attached to a target protein; have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis; DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins; however; in rare cases; conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin); it also has distinct roles; such as in activation of protein kinases; and in signaling.
- Gene Details:
- ubiquitin A-52 residue ribosomal protein fusion product 1
- Protein Details:
- Ubiquitin-60S ribosomal protein L40
- Sensitivity:
- < 0.116 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
