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Assay Kits & ELISAs

TSG101 ELISA Kit

Product Sizes
96 Wells
£868.00
OKCD01703-96WELLS
About this Product
SKU:
OKCD01703
Additional Names:
ESCRT-I complex subunit TSG101;TSG10;tumor susceptibility gene 10;tumor susceptibility gene 101;tumor susceptibility gene 101 protein;tumor susceptibility protein;VPS23.
Extra Details:
Component of the ESCRT-I complex; a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP; CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426).
Gene Details:
tumor susceptibility 101
Protein Details:
Tumor susceptibility gene 101 protein
Sensitivity:
< 0.114 ng/mL
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C|-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs