ADRBK1 ELISA Kit
Product Sizes
96 Wells
£868.00
OKCD01648-96WELLS
About this Product
- SKU:
- OKCD01648
- Additional Names:
- ADRBK1;adrenergic beta receptor kinase 1;BARK1;beta-adrenergic receptor kinase 1;beta-ARK-1;BETA-ARK1;G-protein coupled receptor kinase 2.
- Extra Details:
- Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors; probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PubMed:19306925; PubMed:19715378). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity).
- Gene Details:
- G protein-coupled receptor kinase 2
- Protein Details:
- Beta-adrenergic receptor kinase 1
- Sensitivity:
- < 0.125 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
