Adam10 High Sensitivity ELISA Kit
Product Sizes
96 Wells
£868.00
OKCD01334-96WELLS
About this Product
- SKU:
- OKCD01334
- Additional Names:
- 1700031C13Rik;a disintegrin and metalloprotease domain (ADAM) 10;disintegrin and metalloproteinase domain-containing protein 10;kuz;kuzb;kuzbanian;kuzbanian protein homolog;MADM;mammalian disintegrin-metalloprotease.
- Extra Details:
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins; including heparin-binding epidermal growth-like factor; ephrin-A2; CD44; CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP) at '687-Lys-|-Leu-688' (By similarity). Contributes to the normal cleavage of the cellular prion protein (By similarity). Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles; suggesting a vesicle-based protease activity (By similarity). Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis (PubMed:9244301). Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form (By similarity). Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B (By similarity). May regulate the EFNA5-EPHA3 signaling (By similarity).
- Gene Details:
- a disintegrin and metallopeptidase domain 10
- Protein Details:
- Disintegrin and metalloproteinase domain-containing protein 10
- Sensitivity:
- 3.7 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
