ATF4 ELISA Kit
Product Sizes
96 Wells
£901.00
OKCD01199-96WELLS
About this Product
- SKU:
- OKCD01199
- Additional Names:
- Activating transcription factor 4;activating transcription factor 4 (tax-responsive enhancer element B67);activating transcription factor ATF-4;cAMP-dependent transcription factor ATF-4;cyclic AMP-dependent transcription factor ATF-4;rATF-4.
- Extra Details:
- Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'); a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP; activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes (By similarity).
- Gene Details:
- activating transcription factor 4
- Protein Details:
- Cyclic AMP-dependent transcription factor ATF-4
- Sensitivity:
- < 28 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
