TICAM1 ELISA Kit
Product Sizes
96 Wells
£901.00
OKCD01142-96WELLS
About this Product
- SKU:
- OKCD01142
- Additional Names:
- AW046014;AW547018;TICAM;TICAM-1;TIR domain-containing adapter molecule 1;TIR domain-containing adapter protein inducing IFN-beta;TIR domain-containing adaptor inducing interferon-beta;toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta;Tr;TRIF.
- Extra Details:
- Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation; and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1; TRAF6 and RIPK1; which in turn; lead to the activation of transcription factors IRF3 and IRF7; NF-kappa-B and FADD respectively.
- Gene Details:
- toll-like receptor adaptor molecule 1
- Protein Details:
- TIR domain-containing adapter molecule 1
- Sensitivity:
- < 22.9 pg/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
