ABCA4 ELISA Kit
Product Sizes
96 Wells
£868.00
OKCD00914-96WELLS
About this Product
- SKU:
- OKCD00914
- Additional Names:
- ABC10;ABCR;ARMD2;ATP binding cassette transporter;ATP-binding cassette sub-family A member 4;ATP-binding cassette transporter; retinal-specific;ATP-binding cassette; sub-family A (ABC1); member 4;ATP-binding transporter; retina-specific;CORD3;FFM;photoreceptor rim protein;retinal-specific ATP-binding cassette transporter;retinal-specific phospholipid-transporting ATPase ABCA4;retina-specific ABC transporter;RIM ABC transporter;RIM protein;RMP;RP19;stargardt disease protein;STGD;STGD1.
- Extra Details:
- In the visual cycle; acts as an inward-directed retinoid flipase; retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface; ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse; removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
- Gene Details:
- ATP binding cassette subfamily A member 4
- Protein Details:
- Retinal-specific ATP-binding cassette transporter
- Sensitivity:
- < 0.128 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
