RUNX2 ELISA Kit
Product Sizes
96 Wells
£962.00
OKCA02591-96WELLS
About this Product
- SKU:
- OKCA02591
- Additional Names:
- RP1-166H4.1; AML3; CBFA1; CCD; CCD1; MGC1;20022; MGC1;20023; OSF2; PEA2aA; PEBP2A1; PEBP2A2; PEBP2aA; PEBP2aA1; CBF-alpha 1; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core-binding factor alpha A
- Extra Details:
- Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site; 5'-PYGPYGGT-3'; of a number of enhancers and promoters; including murine leukemia virus; polyomavirus enhancer; T-cell receptor enhancers; osteocalcin; osteopontin; bone sialoprotein; alpha 1(I) collagen; LCK; IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation. In osteoblasts; supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
- Protein Details:
- Runt-related transcription factor 2
- Sensitivity:
- 0.78 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store as indicated in product manual.
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
