CD5L ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£788.00
OKBB01545-96WELLS
About this Product
- SKU:
- OKBB01545
- Additional Names:
- CD5 antigen-like;Apoptosis inhibitor expressed by macrophages ;hAIM ;CT-2 ;IgM-associated peptide ;SP-alpha ;CD5L;API6;UNQ203/PRO229 ;
- Extra Details:
- CD5 antigen-like; also known as Sp alpha and AIM; is a protein that in humans is encoded by the CD5L gene. It is mapped to 1q21-q23 by fluorescence in situ hybridization. It is found that Aim expression is induced in mouse macrophages in response to loading with highly oxidized low density lipoprotein (oxLDL); and that Aim is expressed in foam cells within atherosclerotic lesions. Both the expression of Aim in lesions and its induction by oxLDL require Lxr /Rxr heterodimers. Aim-null macrophages are highly susceptible to oxLDL-induced apoptosis in vitro and undergo accelerated apoptosis in atherosclerotic lesions in vivo. Double knockout of Aim and Ldlr reduce atherosclerotic lesions. Therefore; it is concluded that AIM expression protects macrophages from apoptosis within atherosclerotic lesions; promoting early lesion development.
- Gene Details:
- CD5 antigen-like
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: S20-G347
- Protein Details:
- CD5 antigen-like
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
