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Assay Kits & ELISAs

Bmp10 ELISA Kit

Product Sizes
96 wells/kit; with removable strips.
£1096.00
OKBB01237-96WELLS
About this Product
SKU:
OKBB01237
Additional Names:
Bone morphogenetic protein 10; BMP-10; BMP10
Extra Details:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. This gene is mapped to 4q34. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life.  BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation.  It can signal through various receptor complexes usually containing BMPR-1A; BMPR-1B; ALK1; ALK3; or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors; including SMAD1; SMAD5; or SMAD8; but can also induce SMAD independent processes.  BMP-10 is structurally related to BMP-9; and both can inhibit endothelial cell proliferation and migration.  Recombinant human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits; which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.
Gene Details:
bone morphogenetic protein 10
Immunogen:
Expression system for standard: NS0; Immunogen sequence: N314-R421
Protein Details:
Bone morphogenetic protein 10
Sensitivity:
<10 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs