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Assay Kits & ELISAs

Bmp10 ELISA Kit

Product Sizes
96 wells/kit; with removable strips.
£1096.00
OKBB01236-96WELLS
About this Product
SKU:
OKBB01236
Additional Names:
Bone morphogenetic protein 10; BMP-10; BMP10
Extra Details:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. This gene is mapped to 6; 6 D1. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life.  BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation.  It can signal through various receptor complexes usually containing BMPR-1A; BMPR-1B; ALK1; ALK3; or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors; including SMAD1; SMAD5; or SMAD8; but can also induce SMAD independent processes.  BMP-10 is structurally related to BMP-9; and both can inhibit endothelial cell proliferation and migration.  Recombinant human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits; which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.
Gene Details:
bone morphogenetic protein 10
Immunogen:
Expression system for standard: NS0; Immunogen sequence: N314-R421
Protein Details:
Bone morphogenetic protein 10
Sensitivity:
<10 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs