ADA ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00997-96WELLS
About this Product
- SKU:
- OKBB00997
- Additional Names:
- ada; ADA1; ADA 1; Adenosine aminohydrolase; Adenosine deaminase
- Extra Details:
- Adenosine Deaminase (also known as adenosine aminohydrolase; or ADA) is an enzyme involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. ADA in humans is involved in the development and maintenance of the immune system. However; ADA association has also been observed with epithelial cell differentiation; neurotransmission; and gestation maintenance. It has also been proposed that ADA; in addition to adenosine breakdown; stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins. Adenosine deaminase deficiency leads to pulmonary fibrosis; suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them. It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha; which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress.
- Gene Details:
- adenosine deaminase
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: A2-L363
- Protein Details:
- Adenosine deaminase
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
