CASP3 ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00981-96WELLS
About this Product
- SKU:
- OKBB00981
- Additional Names:
- CASP-3; CASP3; CASP 3; Caspase-3; Caspase3; Caspase 3; SCA-1; SCA 1; SCA1
- Extra Details:
- Caspase-3 is a caspase protein that is encoded by the CASP3 gene. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 6; 7 and 9; and the protein itself is processed by caspases 8; 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein; which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
- Gene Details:
- caspase 3
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: S29-D175 & A183-H277
- Protein Details:
- Caspase-3
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
