BMP4 ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00691-96WELLS
About this Product
- SKU:
- OKBB00691
- Additional Names:
- Bone morphogenetic protein 4;BMP-4;Bone morphogenetic protein 2B;BMP-2B;BMP4;BMP2B; DVR4;
- Extra Details:
- Bone morphogenetic protein 4 is a protein that in humans is encoded by the BMP4 gene which is located to 14q22-q23.1; The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. BMP4 is a polypeptide belonging to the TGF-beta superfamily of proteins. It; like other bone morphogenetic proteins; is involved in bone and cartilage development; specifically tooth and limb development and fracture repair. It has been shown to be involved in muscle development; bone mineralization; and uteric bud development. BMP4 has also been implicated in Fibrodysplasia Ossificans Progressiva in which it is underexpressed. In monkey primate embryonic development; BMP4 is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP4 is secreted from the dorsal portion of the notochord; and it acts in concert with sonic hedgehog(released from the ventral portion of the notochord) to establish a dorsal-ventral axis for the differentiation of later structures. BMP4 stimulates differentiation of overlying ectodermal tissue. Inhibition of the BMP4 signal(by chordin; noggin; or follistatin) causes the ectoderm to differentiate into the neural plate. The standard product used in this kit is recombinant BMP-4 with the molecular mass of 26KDa.
- Gene Details:
- Bone morphogenetic protein 4
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: S293-R408
- Protein Details:
- Bone morphogenetic protein 4
- Sensitivity:
- <4 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
