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Assay Kits & ELISAs

BMP2 ELISA Kit

Product Sizes
96 wells/kit; with removable strips.
£756.00
OKBB00684-96WELLS
About this Product
SKU:
OKBB00684
Additional Names:
Bone morphogenetic protein 2 ;BMP2 ;
Extra Details:
Bone morphogenetic protein-2(BMP-2; BMP 2A) belongs to the transforming growth factor beta(TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis; but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis; whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase(MAPK); which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins(BMPs) are known to promote osteogenesis; and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant Bovine BMP-2; constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.
Gene Details:
bone morphogenetic protein 2
Immunogen:
Expression system for standard: CHO; Immunogen sequence: Q283-R396
Protein Details:
Bone morphogenetic protein 2
Sensitivity:
<2 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs