BDNF ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£630.00
OKBB00676-96WELLS
About this Product
- SKU:
- OKBB00676
- Additional Names:
- Brain-derived neurotrophic factor;BDNF;Abrineurin;BDNF;
- Extra Details:
- Brain-derived neurotrophic factor(BDNF) is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is a secreted protein with the molecular weight of 27.8kDa; consisting of 247 amino acids. It is known to promote neuronal survival and differentiation. BDNF shares substantial amino acid sequence identity with nerve growth factor(NGF). BDNF and neurotrophin-3(NT-3) are two recently cloned neurotrophic factors that are homologous to NGF. mRNA products of the BDNF and NT-3 genes are detected in the adult rabbit brain; suggesting that these proteins are involved in the maintenance of the adult nervous system. BDNF and other neurotrophins are critically involved in long-term potentiation(LTP). BDNF-mediated LTP is induced postsynaptically. BDNF has trophic effects on serotonergic(5-HT) neurons in the central nervous system. BDNF has an essential maintenance function in the regulation of anxiety-related behavior and in food intake through central mediators in both the basal and fasted state. It plays a role in treating breathing disorders such as respiratory insufficiency after spinal injury. The mature form of BDNF is identical in all mammals examined; and the gene encoding rabbit BDNF to chromosome 11; band p13.
- Gene Details:
- Brain-derived neurotrophic factor
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: H129-R247
- Protein Details:
- Brain-derived neurotrophic factor
- Sensitivity:
- <15 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
