Complement C5a ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00646-96WELLS
About this Product
- SKU:
- OKBB00646
- Additional Names:
- anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5; CO5_HUMAN; complement C5; Complement C5 alpha chain; Complement component 5; CPAMD4; ECLZB
- Extra Details:
- C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement; which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide; C5a; which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity; is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component; and this complex is the basis for formation of the membrane attack complex; which includes additional complement components. Mutations in this gene cause complement component 5 deficiency; a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.
- Gene Details:
- complement component 5
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: T678-R751
- Protein Details:
- Complement C5
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
