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Assay Kits & ELISAs

ADAM12 ELISA Kit

Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00585-96WELLS
About this Product
SKU:
OKBB00585
Additional Names:
ADA12_HUMAN; ADAM 12; ADAM metallopeptidase domain 12; ADAM12; Disintegrin and metalloproteinase domain-containing protein 12; MCMP; MCMPMltna; Meltrin-alpha; MLTN; MLTNA
Extra Details:
ADAM12 (Disintegrin and metalloproteinase domain-containing protein 12); also known as MLTN; is an enzyme that in humans is encoded by the ADAM12 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins; and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions; including fertilization; muscle development; and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. By RT-PCR and immunoblot analyses that expression of mouse Adam12 increases during muscle regeneration; while the levels of other ADAMs remain constant. Immunofluorescence analysis revealed staining of small; newly formed muscle fibers in regenerating but not normal adult muscle cells. By using of fluorescence in situ hybridization; the ADAM12 gene is mapped to human chromosome 10q26.3.
Gene Details:
ADAM metallopeptidase domain 12
Immunogen:
Expression system for standard: CHO; Immunogen sequence: R29-S513
Protein Details:
Disintegrin and metalloproteinase domain-containing protein 12
Sensitivity:
<10 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs