MFGE8/Lactadherin ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00535-96WELLS
About this Product
- SKU:
- OKBB00535
- Additional Names:
- BA46; Breast epithelial antigen BA46; Contains Medin; EDIL1; HMFG; hP47; HsT19888; Lactadherin; Lactadherin [Precursor]; Medin; MFG E8; MFG-E8; MFGE8; MFGM; MFGM_HUMAN; Milk fat globule EGF factor 8; Milk fat globule EGF factor 8 protein; Milk fat globule-EGF factor 8; O acetyl disialoganglioside synthase; OAcGD3S; SED1; SPAG10; Sperm associated antigen 10; Sperm surface protein hP47
- Extra Details:
- MFGE8 (Milk Fat Globule-Egf Factor 8); also called as Lactadherin or SED1; is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates; including mammals as well as birds. By fluorescence in situ hybridization; the MFGE8 gene was mapped to chromosome 15q25. MFGE8 is a factor that links apoptotic cells to phagocytes. It specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8; when engaged by phospholipids; bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. It showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay; they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon (PRKCE)-dependent mechanism.
- Gene Details:
- milk fat globule-EGF factor 8 protein
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: L24-C387
- Protein Details:
- Lactadherin
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
