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Assay Kits & ELISAs

Furin ELISA Kit

Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00459-96WELLS
About this Product
SKU:
OKBB00459
Additional Names:
Dibasic processing enzyme; Dibasic-processing enzyme; FES upstream region; FUR; FURIN; Furin membrane associated receptor protein; FURIN_HUMAN; PACE; Paired basic amino acid residue cleaving enzyme; Paired basic amino acid residue-cleaving enzyme; PCSK3; Proprotein convertase subtilisin/kexin type 3; SPC1
Extra Details:
Furin (Fur); also known as PACE; is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus; where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance
Gene Details:
furin (paired basic amino acid cleaving enzyme)
Immunogen:
Expression system for standard: NS0; Immunogen sequence: D108-E715
Protein Details:
Furin
Sensitivity:
<10 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs