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Assay Kits & ELISAs

IL7R/CD127 ELISA Kit

Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00430-96WELLS
About this Product
SKU:
OKBB00430
Additional Names:
CD 127; CD127; CD127 antigen; CDw127; IL 7R alpha; IL 7R; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; IL7R; IL7RA; IL7RA_HUMAN; IL7Ralpha; ILRA; Interleukin 7 receptor alpha chain; Interleukin 7 receptor; Interleukin 7 receptor isoform H5 6; Interleukin-7 receptor subunit alpha
Extra Details:
The interleukin-7 receptor (IL7R) is a protein found on the surface of cells. It is mapped to 5p13.2. The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor; gamma chain (IL2RG); which is a common gamma chain shared by the receptors of various cytokines; including interleukine 2; 4; 7; 9; and 15. IL7R has been shown to play a critical role in the development of immune cells called lymphocytes-specifically in a process known as V (D)J recombination. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene; by STAT5 and histone acetylation. What's more; IL7R antagonism is efficacious in treatment of EAE through its effects on Th17 cells and is a potential treatment for MS.
Gene Details:
interleukin 7 receptor
Immunogen:
Expression system for standard: NS0; Immunogen sequence: E21-D239
Protein Details:
Interleukin-7 receptor subunit alpha
Sensitivity:
<10 pg/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Supplier:
Aviva Systems Biology
Type:
Assay Kits: ELISAs