BAFF ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£630.00
OKBB00298-96WELLS
About this Product
- SKU:
- OKBB00298
- Additional Names:
- B lymphocyte stimulator; B-cell-activating factor; BAFF; BLyS; CD257; Dendritic cell-derived TNF-like molecule; soluble form; TALL-1; TN13B_HUMAN; TNF- and APOL-related leukocyte expressed ligand 1; TNFSF13B; Tumor necrosis factor ligand superfamily member 13b
- Extra Details:
- BAFF was regularly detected by enzyme-linked immunosorbent assay in brain tissue lysates and in normal spinal fluid; and in astrocytes by double fluorescence microscopy. BAFF was localized in astrocytes close to BAFF-R-expressing immune cells. BAFF receptors were strongly expressed in situ in primary central nervous system (CNS) lymphomas.1 The TNF superfamily member B cell-activating factor (BAFF) plays an important role in humoral immunity and in autoimmune diseases; including RA.Local BAFF gene targeting inhibited proinflammatory cytokine expression; suppressed generation of plasma cells and Th17 cells; and markedly ameliorated joint pathology.2 The B cell activating factor BAFF (BlyS/TALL-1/zTNF4) is a tumor necrosis factor (TNF)-related ligand that promotes B cell survival and binds to three receptors (BCMA; TACI; and the recently described BAFF-R).3 Human BAFF was mapped to chromosome 13q32-34.4 The standard used in this kit is recombinant soluble human BAFF (A134-L295) with the molecular mass of 19.6KDa.
- Gene Details:
- tumor necrosis factor (ligand) superfamily; member 13b
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: A134-L285
- Protein Details:
- Tumor necrosis factor ligand superfamily member 13B
- Sensitivity:
- <2 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
