TRAIL ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£766.00
OKBB00266-96WELLS
About this Product
- SKU:
- OKBB00266
- Additional Names:
- Apo 2 ligand; APO2L; CD253; Protein TRAIL; TL2; TNF related apoptosis inducing ligand; Tumor necrosis factor ligand superfamily member 10
- Extra Details:
- In the field of cell biology; TNF-related apoptosis-inducing ligand (TRAIL); is a protein which functions as a ligand which induces the process of cell death called apoptosis. TRAIL has also been designated CD253 (cluster of differentiation 253).Tumor necrosis factor (TNF) family cytokines function as prominent mediators of immune regulation and the inflammatory response. Most TNF family cytokines are expressed as type II transmembrane proteins; with homology confined to approximately 150 C-terminal residues. The TNF ligands interact with a parallel family of receptors. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII). The process of apoptosis is caspase-8-dependent. Caspase-8 activates downstream effector caspases including procaspase-3; -6; and -7; leading to activation of specific kinases. TRAIL also binds the receptors DcR1 and DcR2; which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). The standard product used in this kit is recombinant human TRAIL with the molecular mass of 21KDa. It is expressed from the amino acids ectoderm T95--G281.
- Gene Details:
- tumor necrosis factor (ligand) superfamily; member 10
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: T95-G281
- Protein Details:
- Tumor necrosis factor ligand superfamily member 10
- Sensitivity:
- <1 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
