TNFRSF1A ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£788.00
OKBB00264-96WELLS
About this Product
- SKU:
- OKBB00264
- Additional Names:
- CD120a; FPF; p55; p55 R; p60; p65; TBP1; TBPI; TNF R; TNF R I; TNF R55; TNF-R1; TNF-RI; TNFAR; TNFR I; TNFR1; TNFR55; TNFR60; TNFRI; TNFRSF1A; TNR1A_HUMAN; Tumor necrosis factor alpha receptor; Tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A; membrane form; Tumor necrosis factor receptor type I; Tumor necrosis factor-binding protein 1
- Extra Details:
- TNFsRâ… (also known as Solube tumor necrosis factor receptor 1) is a cytokine receptor that binds tumor necrosis factors (TNF). In contrast; the p60 (TNFRSF1A) and p80 (TNFRSF1B) TNFA receptors self-assemble through a distinct functional domain in the TNFR extracellular domain; termed the pre-ligand assembly domain (PLAD); in the absence of ligand. Deletion of the PLAD results in monomeric presentation of p60 or p80. Flow cytometric analysis showed that efficient TNFA binding depends on receptor self-assembly. They also found that other members of the TNF receptor superfamily; including the extracellular domains of TRAIL (TNFRSF10A); CD40; and FAS (TNFRSF6); all self-associate but do not interact with heterologous receptors. By Southern blot analysis of human/Chinese hamster somatic cell hybrid DNA; the TNFR1 gene was mapped to 12pter-cen. And by nonradioactive in situ hybridization that the type 1 receptor (the p55 TNF receptor) is encoded by a gene located on chromosome 12p13.2.
- Gene Details:
- tumor necrosis factor receptor superfamily; member 1A
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: L30-T211
- Protein Details:
- Tumor necrosis factor receptor superfamily member 1A
- Sensitivity:
- <1 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
