IL10 ELISA Kit
Product Sizes
96 wells/kit; with removable strips.
£701.00
OKBB00193-96WELLS
About this Product
- SKU:
- OKBB00193
- Additional Names:
- CSIF; Cytokine synthesis inhibitory factor; GVHDS; IL 10; IL-10; IL10; IL10_HUMAN; IL10A; Interleukin 10; Interleukin-10; Interleukin10; MGC126450; MGC126451; T cell growth inhibitory factor; TGIF
- Extra Details:
- Interleukin-10; also called cytokine synthesis inhibitory factor; is implicated in tumorigenesis; and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production.1 IL-10 is an important cytokine with anti-inflammatory; anti-immune; and antifibrotic functions.2 It is also an important regulatory cytokine whose involvement extends into diverse areas of the human immune system.3 IL-10 is a recently described natural endogenous immunosuppressive cytokine that has been identified in human; murine; and other organisms. IL-10 significantly affects chemokine biology; because human IL-10 inhibits chemokine production and is a specific chemotactic factor for CD8+ T cells. It suppresses the ability of CD4+ T cells; but not CD8+ T cells; to migrate in response to IL-8.4 Interleukin-10 gene polymorphisms and interleukin-10 production capability may contribute to the development of skin squamous cell carcinomas after renal transplantation.1 The interleukin-10 locus contributes to the heritability of psoriasis susceptibility.5 With regard to sudden infant death; IL-10 is of special interest. This is an immunoregulatory cytokine that plays an important role in the development of infectious disease.6 The mIL-10 gene is mapped to mouse chromosome 1 and the hIL-10 gene is also mapped to human chromosome 1.7 The standard product used in this kit is recombinant human IL-10; consisting of 160 amino acids with the molecular mass of 18.6KDa.
- Gene Details:
- interleukin 10
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: S19-N178
- Protein Details:
- Interleukin-10
- Sensitivity:
- <0.5 pg/ml
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
